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Recommend sufferers not to adjust the dose of acetaminophen and codeine phosphate tablets without consulting a health practitioner or other healthcare professional.

Dosing mistakes have resulted from confusion among mg and mL when prescribing, dispensing, and administering oral Option; make sure dose is communicated clearly and dispensed precisely

Even though the danger of dependancy in almost any person is unidentified, it may come about in individuals properly prescribed acetaminophen and codeine phosphate tablets. Habit can come about at advisable dosages and In case the drug is misused or abused.

Bodily dependence is really a state that develops as a result of a physiological adaptation in response to recurring drug use, manifested by withdrawal signs and signs or symptoms right after abrupt discontinuation or a big dose reduction of a drug.

Acetaminophen and codeine phosphate tablets are contraindicated for all children young than twelve yrs of age (see CONTRAINDICATIONS).

Codeine brings about a discount in motility connected with a rise in sleek muscle tone during the antrum from the belly and duodenum. Digestion of food stuff within the modest intestine is delayed and propulsive contractions are lowered.

Evaluate each affected person's possibility previous to prescribing and keep track of all clients frequently for the event of such behaviors or conditions.

Long-expression use of opioid medication may well have an effect on fertility (power to have youngsters) in Adult males or Females. It is far from regarded regardless of whether opioid effects on fertility are everlasting.

To scale back the risk of respiratory melancholy, appropriate dosing and titration of acetaminophen and codeine phosphate tablets are vital (see DOSAGE AND ADMINISTRATION).

If withdrawal symptoms come up, it could be important to pause the taper for any time period or increase the dose with the opioid analgesic to your former dose, and then proceed by using a slower taper. Also, click here Examine people for virtually any changes in mood, emergence of suicidal thoughts, or use of other substances.

If a CYP3A4 inducer is discontinued, contemplate acetaminophen and codeine phosphate tablets dosage reduction and Consider clients at click here Repeated intervals for signs of respiratory depression and sedation.

Instruct sufferers to discontinue acetaminophen and codeine phosphate tablets read more instantly and search for health care care should get more info they expertise these symptoms. Will not prescribe acetaminophen and website codeine phosphate tablets for individuals with acetaminophen allergy (see Safety measures, Details for Patients/Caregivers).

pregnant or intending to grow to be pregnant. Extended use of Acetaminophen and Codeine Phosphate Tablets, USP through pregnancy could cause withdrawal signs in your new child baby that would be existence-threatening Otherwise acknowledged and treated.

Neonatal Opioid Withdrawal Syndrome: Extended use in the course of pregnancy can lead to neonatal opioid withdrawal syndrome, which can be life-threatening if not identified and taken care of, and involves administration Based on protocols formulated by neonatology professionals.